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human pd 1 mofc protein  (ACROBiosystems)


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    Structured Review

    ACROBiosystems human pd 1 mofc protein
    Human Pd 1 Mofc Protein, supplied by ACROBiosystems, used in various techniques. Bioz Stars score: 95/100, based on 93 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pd+1+mofc+protein/Human+PD-1+%2F+PDCD1+Protein%2C+His+Tag/us12583922-942-12-15
    Average 95 stars, based on 93 article reviews
    human pd 1 mofc protein - by Bioz Stars, 2026-09
    95/100 stars

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    Concentration Assay:

    Article Title: Bispecific antibodies targeting CD47 and PD-L1 and methods of use thereof
    Article Snippet: TABLE 4 PD-1 blocking potency of selected CD47xPD-L1 bispecific antibodies and anti-PD-L1 atezolizumab on human PD-L1 transfected CHO cells PD-1 inhibition potency Antibody name (IC50 in nM) Atezolizumab 0.02 (bivalent anti-PD-L1) S37 bsAb 0.14 S79 bsAb 0.03 S94 bsAb 0.05 S100 bsAb 0.07 S28 bsAb 0.12 E. Binding to CD47-Positive Tumor Cells The CD47 binding on cells of an exemplary CD47×PD-L1 bsAb was studied by flow cytometry using human Raji (ATCC (American Type Culture Collection); CCL-86) and Nalm-6 (ATCC (American Type Culture Collection); CRL-3273) tumor cell lines and CHO cells as a negative control.



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    Structural basis for blocking the PD-1/PD-L1 interaction by the anti-PD-L1 S79 fab.

    Journal: mAbs

    Article Title: Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1

    doi: 10.1080/19420862.2024.2362432

    Figure Lengend Snippet: Structural basis for blocking the PD-1/PD-L1 interaction by the anti-PD-L1 S79 fab.

    Article Snippet: As detection reagent, a mix of 0.1 µg/mL of human PD-1-moFc protein (ACROBiosystems, #PD1-H5255) for CHO-PD-L1 cells, or 0.2 µg/mL of high-affinity human PD-1-moFc protein (produced in-house, based on the high affinity consensus PD-1 variant published in Maute et al . for HT-1080 cells and AF647-conjugated goat anti-mouse IgG, Fcγ fragment specific (Jackson ImmunoResearch, #115-605-071, dilution 1:5000) was added for 3 hours at RT before reading.

    Techniques: Blocking Assay